Tesamorelin

Growth Hormone Optimization Subcutaneous Injectable

Tesamorelin is an FDA-approved GHRH analog with the strongest clinical evidence for reducing visceral fat — the metabolically dangerous fat that wraps around organs. It also shows promise for cognitive function in aging and is widely used in perimenopausal body-composition protocols.

Best for: Stubborn abdominal fat, metabolic syndrome, cognitive resilience, peri-menopausal body composition shifts.

Lab-guided protocolsPersonalized dosingProvider-led oversightIn-clinic & telehealth Lab-guided protocolsPersonalized dosingProvider-led oversightIn-clinic & telehealth

The questions, answered.

  • Reduces visceral adipose tissue — strongest clinical evidence of any peptide.
  • Improves lipid panel (triglycerides, HDL) over months.
  • Cognitive benefits in aging populations in clinical trials.
  • Body composition: lean mass preservation alongside fat loss.
  • FDA-approved for HIV-associated lipodystrophy (off-label for body comp).
  • Supports metabolic health markers alongside lifestyle interventions.
  • GHRH receptor agonism: sustained natural GH release pattern.
  • Visceral fat lipolysis: uniquely targets metabolically active fat depots.
  • IGF-1 elevation to youthful range.
  • Cognitive support likely via improved cerebral metabolism.
  • Weeks 1–2: Initial fluid shifts settle; subtle changes in waist circumference begin.
  • Weeks 4–6: Measurable visceral fat reduction; lipid panel improves.
  • Weeks 8–12: Substantial body composition and metabolic gains; lab markers consolidate.
  • Injection-site reactions: redness, itching, mild bruising.
  • Joint stiffness or fluid retention: often resolves in 4–6 weeks.
  • Mild glucose elevation: monitor with labs.
  • Headache or flushing: usually self-limiting.
  • Dose nightly to align with natural GH pulse.
  • Pair with strength training for compounded body composition effect.
  • Monitor fasting glucose and A1C with periodic labs.
  • Hydrate well to minimize fluid retention.
  • Active malignancy without oncology oversight.
  • Pituitary disorders — discuss with endocrinology.
  • Pregnancy or breastfeeding.
  • Severe insulin resistance: requires careful glucose monitoring.
Important Note The FDA's position on peptides continues to evolve. Availability of specific compounds may change, and not all peptides discussed are currently offered at every visit. Book a consultation with our provider team to discuss your goals, current options, and what's appropriate for you.

Layered with intention.

— Begin

Precision protocols.
Designed around you.

Every TAI peptide protocol is lab-guided and provider-led. Start with biomarkers, design around your goals, refine at intervals. Available in-clinic and via telehealth.

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