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KPV

Repair & Recovery · Immune Oral Capsule / Topical / Injectable

KPV is a tripeptide (lysine-proline-valine) derived from alpha-MSH, with potent anti-inflammatory activity. It modulates immune cell behavior without suppressing the immune system — making it particularly useful for chronic inflammatory conditions where you want to calm the fire without dimming the flame entirely.

Best for: IBD, colitis, chronic skin inflammation, autoimmune flares, histamine issues.

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Lab-guided protocolsPersonalized dosingProvider-led oversightIn-clinic & telehealth Lab-guided protocolsPersonalized dosingProvider-led oversightIn-clinic & telehealth
Frequently Asked
What clients want to know about KPV

The questions, answered.

  • Calms gut inflammation in IBD, colitis, and food-sensitivity-related flares.
  • Reduces skin inflammation in eczema, psoriasis-adjacent issues, and reactive skin.
  • Modulates without suppressing — preserves the immune response while calming overreaction.
  • Antimicrobial properties: helps balance microbiome composition.
  • Supports histamine regulation for clients with mast cell or histamine-driven symptoms.
  • Well tolerated long-term at therapeutic doses.
  • NF-κB pathway inhibition: downregulates the master inflammatory transcription factor.
  • Cytokine modulation: reduces IL-6, TNF-α, and other inflammatory signals.
  • Mast cell stabilization: calms histamine release in reactive tissues.
  • Antimicrobial activity against opportunistic gut pathogens.
  • Weeks 1–2: Initial reduction in flare intensity; skin and gut symptoms begin to soften.
  • Weeks 4–6: Notable symptom resolution for many; baseline inflammation markers improve.
  • Weeks 8–12: Sustained remission for many chronic-inflammatory clients; long-term protocol established.
  • Mild GI changes when used orally — typically subside within a week.
  • Minor injection-site reaction if administered subcutaneously.
  • Transient lightheadedness in sensitive individuals.
  • Take oral capsules with food to optimize absorption and minimize GI changes.
  • Pair with BPC-157 for combined gut barrier and inflammatory support.
  • Track symptoms in a journal — anti-inflammatory effects compound week over week.
  • Reassess at 8 weeks with your provider to determine maintenance dose.
  • Active infections requiring full immune response — discuss timing with your provider.
  • Pregnancy or breastfeeding without medical supervision.
  • Known peptide allergy.
Important Note The FDA's position on peptides continues to evolve. Availability of specific compounds may change, and not all peptides discussed are currently offered at every visit. Book a consultation with our provider team to discuss your goals, current options, and what's appropriate for you.
Related Protocols
Often paired or layered alongside KPV

Layered with intention.

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BPC-157
Body Protective Compound
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TB-500
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GHK-Cu
Copper Peptide
— Begin

Precision protocols.
Designed around you.

Every TAI peptide protocol is lab-guided and provider-led. Start with biomarkers, design around your goals, refine at intervals. Available in-clinic and via telehealth.

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